Guanfacine Normalizes Presynaptic Alpha-2 Adrenoceptors Enrichment and Ameliorates Neuropathic Pain in Type 1 Diabetic Rats

Pharmacology, Toxicology and Pharmaceutical Science

• Alpha 2 Adrenergic Receptor 100%
• Guanfacine 100%
• Neuropathic Pain 100%
• Streptozotocin 50%
• Mechanical Allodynia 50%
• Hyperalgesia 50%
• Insulin Dependent Diabetes Mellitus 25%
• Alpha 2A Adrenergic Receptor 25%
• Western Blot 25%
• Synaptosomal Associated Protein 25 25%
• Diabetes Mellitus 25%
• Analgesic Agent 25%
• Antinociception 25%

Neuroscience

• Neuropathic Pain 100%
• Streptozotocin 50%
• Hyperalgesia 50%
• Allodynia 50%
• Western Blot 25%
• Nociception 25%
• Dorsal Root Ganglion 25%
• Agonist 25%
• Immunofluorescence 25%
• Synaptosomal Associated Protein 25 25%
• Diabetes Mellitus 25%

Medicine and Dentistry

• Peripheral Nervous System 25%
• Western Blot 25%
• Brainstem 25%
• Central Nervous System 25%
• Pons 25%
• Dorsal Root Ganglion 25%
• Immunofluorescence 25%